Longitudinal course of bone health from infancy to mid-adulthood in preterm and term-born individuals.

ABSTRACT: Preterm birth is associated with various health consequences. However, the long-term impact on bone health remains unclear. This study compares bone health from infancy into mid-adulthood between preterm and term-born individuals and explores potential association with fracture status. Data from the Zurich Longitudinal Studies were analyzed, including preterm and term-born individuals (enrolled 1974-1979). Bone health was measured longitudinally using the Bone Health Index (BHI) from hand X-rays analyzed by BoneXpert. Fracture history was obtained through parental interviews and self-reports. Generalized estimating equation models evaluated BHI over age, adjusting for age, sex, preterm and fracture status. 1582 X-rays from 95 term and 120 preterm individuals, across 17 time points (3 month

SUBMITTER: Brecher J 

PROVIDER: S-EPMC12749154 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature