Isolation and reactivity of sodium benzyl cations.

ABSTRACT: Carbanions are an important class of reactive species used as nucleophiles in C-C bond-forming reactions. Such reactive carbanions are generated by deprotonating relatively acidic C-H bonds using strong bases like sodium/potassium hydroxides or amides. Lochmann-Schlosser base, consisting of a mixture of alkyl lithium reagents and heavier alkali metal alkoxides, is widely used for the metalation of organic compounds via the deprotonation of weakly acidic C-H bond. The aggregation of alkoxides makes it challenging to understand the course of the reaction, demanding the consideration of molecular compounds as alternatives to sodium/potassium alkoxides. Here, we demonstrate the development of new organosodium reagents using molecular compounds as alternatives to oligomeric sodium/potassium alk

SUBMITTER: Kundu S 

PROVIDER: S-EPMC12749772 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature