Efficacy, psychological and physical adverse effects of isotretinoin in the treatment of acne: a cross-sectional study from Syria.

ABSTRACT: This study aims to evaluate the effectiveness of isotretinoin in the treatment of acne, while also monitoring its associated physical and psychological adverse effects. A descriptive cross-sectional study was conducted using an online questionnaire distributed to individuals who are currently experiencing acne or have experienced it in the past. The questionnaire included items regarding acne severity, type and duration of treatment, adherence, side effects and overall satisfaction. Data were statistically analyzed. A total of 377 participants, aged ≥ 15 years, were included in the study. 89.1% of them followed isotretinoin treatment, of whom 316 found an overall improvement (262 as marked). Side effects were experienced by 309 with most commonly reported ones were physical (supplementary

SUBMITTER: Barakat A 

PROVIDER: S-EPMC12749884 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature