Association of surrogate indices of insulin resistance with hypertension: a cross-sectional analysis from PERSIAN Dena cohort study (PDCS).

ABSTRACT: Early detection of hypertension remains challenging due to its asymptomatic nature and limited screening tools. While surrogate indices of insulin resistance (IR) have emerged as potential screening tools for various metabolic disorders, their predictive value for hypertension remains unclear, particularly in different demographic groups. In this cross-sectional study, we analyzed data from 1,840 adults (aged 35-70 years) participating in the PERSIAN Dena cohort study (PDCS). Eight IR indices were evaluated: triglyceride-to-high-density lipoprotein cholesterol ratio (TG/HDL-C), visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride-glucose index (TyG), TyG-body mass index (TyG-BMI), TyG-waist circumference (TyG-WC), metabolic score for insulin resistance (METS-IR),

SUBMITTER: Hosseini A 

PROVIDER: S-EPMC12749894 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature