The effect of postoperative chemotherapy on survival outcomes and a nomogram for predicting overall survival in chondroblastic osteosarcoma.

ABSTRACT: The analysis of chondroblastic osteosarcoma (CBO) was conducted using data from the Surveillance, Epidemiology, and End Results (SEER) database (2000-2019).​ A cohort of 317 surgically treated CBO patients was analyzed, with 261 (82.3%) receiving adjuvant chemotherapy and 56 (17.7%) classified as no/unknown chemotherapy recipients. The median diagnosis year of CBO patients was 2005 and the median follow-up time was 5.25 years (63 months).​​ Kaplan-Meier analysis demonstrated that chemotherapy significantly improved overall survival (OS) (P = 0.011), a finding corroborated after propensity score matching (P = 0.036). Specifically, the 5-year, 10-year, and 15-year overall survival(OS) of patients who received chemotherapy were 52.11%, 35.25%, and 25.29%, respectively. In contrast, the corres

SUBMITTER: Li R 

PROVIDER: S-EPMC12749957 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature