[Ovarian tissue cryopreservation and transplantation: a review of clinical progress in fertility preservation].

ABSTRACT: With the increasing survival rates of cancer patients, the demand for fertility preservation in women has become increasingly prominent. Ovarian tissue cryopreservation and transplantation (OTCT) is an emerging fertility preservation technique that offers a unique advantage over embryo or oocyte cryopreservation, as it does not require ovarian stimulation. This makes it particularly suitable for prepubertal girls requiring urgent gonadotoxic therapy and reproductive-age women who cannot delay cancer treatment. Clinical evidence confirms that OTCT can effectively restore female fertility-especially the potential for natural conception-and restore ovarian endocrine function. The OTCT process involves key steps such as patient evaluation, tissue processing, cryopreservation, and transplantati

SUBMITTER: Chen J 

PROVIDER: S-EPMC12750056 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature