[Advances in ovarian tissue cryopreservation and transplanta-tion for fertility preservation in prepubertal patients].

ABSTRACT: Ovarian tissue cryopreservation and transplantation is currently the only feasible method for preserving both fertility and ovarian endocrine function in prepubertal females. It is indicated for those requiring gonadotoxic therapies such as chemotherapy, radiotherapy, or bone marrow transplantation for malignant diseases, as well as for non-malignant diseases, including immunologic, metabolic, and hematologic benign diseases requiring bone marrow transplantation, and other populations at high risk of premature ovarian insufficiency. The procedure involves laparoscopic retrieval of ovarian tissue, followed by slow-programmed cryopreservation. When the primary disease is cured and fertility or hormonal function restoration is desired, the tissue is thawed and transplanted, most commonly to a

SUBMITTER: Cheng J 

PROVIDER: S-EPMC12750059 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature