Time Trends and Predictors of Gout Remission Over 6 Years.

ABSTRACT:

Objective

This study aims to describe the trends in remission rates over 6 years of follow-up among people with gout taking urate-lowering therapy (ULT) and to identify variables that predict remission.

Methods

A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial, which enrolled people with gout and cardiovascular disease randomized to febuxostat or allopurinol. Gout remission over 6 years of follow-up was measured in participants with at least 1 year of follow-up data using the simplified gout remission definition, requiring the fulfillment of three domains: (1) no gout flares during the past year, (2) at least two serum urate measurements <0.36 mmol/L during the past year, and (3) no to

SUBMITTER: Tabi-Amponsah AD 

PROVIDER: S-EPMC12750121 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature