Different Neuroprotective Activities of Proanthocyanidin-Enriched Fractions of <i>Lotus</i> Species.

ABSTRACT: Flavonoid-rich Lotus species are promising sustainable sources of bioactive phytochemicals due to their adaptability, high biomass production, and symbiosis with nitrogen-fixing Rhizobium spp. Among flavonoids, many beneficial effects for human health, ranging from antioxidant activities to the inhibition of carcinogenesis, are attributed to proanthocyanidins (PAs). This study compared the neuroprotective properties of leaf extracts from PA-rich Lotus corniculatus (Lc), PA-depleted Lotus tenuis (Lt), and Lc × Lt interspecific hybrid (Lh2) with intermediate PA levels. Acetone-soluble and -insoluble fractions from Lc and Lh2 contained flavan-3-ols and PA oligomers, while Lt lacked these compounds. Neuroprotec

SUBMITTER: Ceccarini MR 

PROVIDER: S-EPMC12750242 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature