Eye tracking as a diagnostic tool in Alzheimer's disease, mild cognitive impairment, and related dementias: a systematic review.

ABSTRACT: Alzheimer's disease (AD) pathology begins years before symptoms emerge, making early detection essential. Eye tracking offers a rapid, non-invasive means of identifying early cognitive decline through oculomotor disturbances. This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)- and Population, Intervention, Comparison, and Outcome (PICO)-guided systematic review evaluated studies from PubMed, ACM Digital Library, and Google Scholar on eye tracking in mild cognitive impairment (MCI), AD, and related dementias. Seventy-one studies met the inclusion criteria. Antisaccade tasks consistently distinguished AD and MCI from healthy controls, with impaired accuracy, longer latencies, and reduced gain. Non-saccadic paradigms (e.g., visual search, free viewing) indicated

SUBMITTER: Veron GL 

PROVIDER: S-EPMC12750316 | biostudies-literature | 2026 Jan-Mar

REPOSITORIES: biostudies-literature