The diagnostic and prognostic value of circulating miR-193b-3p on severe pneumonia.

ABSTRACT:

Background

Severe pneumonia (SP) poses a serious threat to patients' lives, and this study aimed to explore the diagnostic and prognostic value of miR-193b-3p on SP, thereby providing novel insights for the clinical management of SP.

Methods

The miR-193b-3p expression was evaluated by PCR. The diagnostic value of miR-193b-3p on SP was assessed by ROC. The association between miR-193b-3p expression and the SP severity was assessed by the correlation analysis. The correlation between miR-193b-3p expression and the survival status of SP patients was evaluated by the Kaplan-Meier survival analysis. Potential independent prognostic factors for SP were predicted by multivariate COX regression analysis. Bioinformatics analysis assessed the possible pathways regulated by miR-193b-3p

SUBMITTER: Liu K 

PROVIDER: S-EPMC12750694 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature