Quantitative evaluation of myocardial work in patients with type 2 diabetes mellitus complicated with nonalcoholic fatty liver by noninvasive pressure-strain loop.

ABSTRACT:

Objective

To quantitatively evaluate myocardial work in patients with type 2 diabetes mellitus (T2DM) complicated with nonalcoholic fatty liver disease (NAFLD) by noninvasive pressure-strain loop (PSL).

Methods

The study included 103 treatment-naive T2DM patients, categorized into three groups based on abdominal ultrasound findings: Group A (T2DM without NAFLD, n = 34), Group B (T2DM with mild NAFLD, n = 37), and Group C (T2DM with moderate to severe NAFLD, n = 32). All patients underwent echocardiography to assess left ventricular structure and systolic function. Apical four-chamber, two-chamber, and three-chamber echocardiographic images were collected. PSL analysis was used to obtain myocardial work parameters, including left ventricular global longitudinal strain (GLS),

SUBMITTER: Tian M 

PROVIDER: S-EPMC12750941 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature