Neonatal characteristics and neurodevelopmental phenotypes in congenital cytomegalovirus.

ABSTRACT:

Background

Children with congenital cytomegalovirus (cCMV) have a wide spectrum of possible neurodevelopmental outcomes.

Objectives

To describe neurodevelopmental (ND) Phenotypes of children with cCMV based on medical, developmental, and behavioral outcomes in childhood, and examine whether birth characteristics were associated with ND Phenotype.

Methods

Caregivers of children with cCMV (N = 242, child aged 12 months to <11 years) completed survey instruments reporting on the child's birth characteristics, reasons for cCMV testing, and present medical, developmental, and behavioral status. Latent Class Analysis was used to derive empirically driven groupings of outcomes, which we called ND Phenotypes. Chi-square analyses and t-tests examined the association between ND

SUBMITTER: Pollick SA 

PROVIDER: S-EPMC12751029 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature