Tracheobronchial adenoid cystic carcinoma: a two-center retrospective analysis of clinical features and survival outcomes.

ABSTRACT:

Background

Tracheobronchial adenoid cystic carcinoma (TACC) is an uncommon gland-type tumor. While prior studies have addressed its clinical features and prognosis, evidence from larger cohorts remains scarce.

Methods

TACC patients treated at Dongzhimen Hospital (DZM) and Emergency General Hospital (EG) between 2010 and 2023 were enrolled. Survival curves were plotted using the Kaplan-Meier method before and after propensity score matching (PSM). The key variables were screened by LASSO regression, and predictive and interaction analysis was done by multifactor Cox regression and accelerated failure time (AFT) models. Overall survival (OS) was the study endpoint.

Results

The median age of 169 TACC patients (EG 144, DZM 25) was 47.8 ± 13.2 years, 50.9% were female, and

SUBMITTER: Hong Q 

PROVIDER: S-EPMC12751139 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature