Prealbumin predicts metachronous liver metastasis in colorectal cancer.

ABSTRACT:

Background

Predicting metachronous liver metastasis (MLM) in colorectal cancer (CRC) is crucial in clinical practice. Studies have shown that prealbumin is linked to recurrence and poor overall survival in various malignancies. This study aims to determine whether prealbumin levels can predict postoperative MLM in CRC patients.

Methods

This study included both a primary cohort and an external validation cohort, recruiting a total of 627 CRC patients from two independent hospitals in China. Clinical characteristics and laboratory measurements were collected prior to surgery. The optimal cut-off value for prealbumin in predicting MLM was determined using a receiver operating characteristic (ROC) curve analysis. The Kaplan-Meier method was employed to estimate the 36-month inci

SUBMITTER: Xie HB 

PROVIDER: S-EPMC12751164 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature