Long-term accrual of conditions following myocardial infarction: a study of disease trajectories in the Wales Multimorbidity e-Cohort.

ABSTRACT:

Background

Improved survivorship following myocardial infarction (MI) has resulted in transferred morbidity to other long-term conditions (LTCs). Understanding of disease accrual over time following MI has been limited by a lack of methodologies that consider real-world complexity. We characterised post-MI multimorbidity trajectories in a real-world population of individuals following MI.

Methods

This population-wide retrospective study comprised all individuals with MI in the Wales Multimorbidity e-Cohort (which included linked primary and secondary care data for 2,902,101 GP-registered residents of Wales; 2005-2019). Single-year post-MI disease clusters and multi-year latent multimorbidity trajectories were constructed from 227 chronic conditions and 62 acute conditions, u

SUBMITTER: Batty JA 

PROVIDER: S-EPMC12751190 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature