Comprehensive assessment beyond eosinophils in eosinophilic esophagitis: an updated network meta-analysis.

ABSTRACT:

Background

The rapid development of therapies for eosinophilic esophagitis (EoE), particularly involving biologics and small molecules, has prompted questions about their roles within current treatment algorithms. We aimed to examine the relative efficacy of novel biologics, small molecules and topical steroids by evaluating clinical, endoscopic, and histological improvements.

Methods

We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and major conference databases for articles published from inception to Jul 1, 2024. Randomized controlled trials (RCTs) evaluating the clinical, endoscopic and histological efficacy of novel biologics, small molecules or topical steroids as induction therapies for patients with EoE were included. A network meta-analys

SUBMITTER: Lyu Y 

PROVIDER: S-EPMC12751226 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature