Novel risk scoring system for predicting intravenous immunoglobulin resistance and coronary artery aneurysm in Thai children with Kawasaki disease.

ABSTRACT:

Background

This study aimed to develop an alternative risk scoring system for intravenous immunoglobulin (IVIG) resistance and coronary artery aneurysm (CAA) development in patients with Kawasaki disease (KD) in Thai population.

Methods

This study is a retrospective and prospective study from January 2012 to September 2024. Data on demographics, clinical features, laboratory parameters, echocardiographic results, and outcomes were analyzed. Multivariable logistic regression was used to identify predictors for IVIG resistance and CAA.

Results

A total of 150 patients diagnosed with KD were enrolled. IVIG resistance occurred in 12.9% of cases. Independent predictors were neutrophil-to-lymphocyte ratio (NLR) ≥ 3.5 (aOR 25.0, 95%CI 2.92-214.3), neutrophil-to-lymphocyte pla

SUBMITTER: Tantikittipisut P 

PROVIDER: S-EPMC12751551 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature