Vitamin D, premature mortality, and life expectancy among US adults.

ABSTRACT:

Background

Vitamin D deficiency is prevailing worldwide and linked to multiple diseases; however, its association with premature mortality remains unknown in the US.

Methods

To investigate the association between serum 25-hydroxyvitamin D or 25(OH)D concentrations and premature mortality and life expectancy in a nationally representative cohort of US adults. We analyzed data of adults aged ≥ 18 years included in the National Health and Nutrition Examination Survey from the Third National Health and Nutrition Examination (NHANES III) (1988 - 1994) and NAHANES (2001 - 2018) with linkage to the National Death Index through December 31, 2019 were investigated. Data were analyzed between July and November in 2024. Serum 25(OH)D was computed as the sum of 25(OH)D3 and 25(OH)D2 con

SUBMITTER: Wang Q 

PROVIDER: S-EPMC12751849 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature