Factors associated with adverse haemodynamic events during the STARRT-AKI trial: a post-hoc secondary analysis.

ABSTRACT:

Introduction

Haemodynamic adverse events related to renal replacement therapy are a complication of all RRT modalities used in the ICU, including intermittent haemodialysis (IHD), sustained low efficiency dialysis (SLED) and continuous renal replacement therapy (CRRT). At present it is unclear which risk factors predispose to HAE and whether these contribute to adverse patient outcomes.

Methods

We performed a secondary analysis of the multinational STARRT-AKI trial to assess factors associated with the occurrence of haemodynamic adverse events (HAE) in patients receiving RRT and whether these HAE were associated with less favourable clinical outcomes. The primary analysis was a multivariable Cox proportional hazards model based on the least absolute shrinkage and selection o

SUBMITTER: Kelly YP 

PROVIDER: S-EPMC12751851 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature