Improved stroke risk stratification in carotid atherosclerosis: integrating intraplaque neovascularization into Carotid Plaque-RADS.

ABSTRACT:

Introduction

This study evaluates whether IPN, as assessed by contrast-enhanced ultrasound (CEUS), enhances stroke risk stratification within the Carotid Plaque-RADS framework.

Methods

We conducted a retrospective analysis of 157 stroke patients between July 2020 and January 2021. IPN grade was assessed using CEUS, and patients were categorized based on the Carotid Plaque-RADS. The recurrence-free survival (RFS) rates were calculated, and the incremental value of incorporating IPN grades into Carotid Plaque-RADS was analyzed.

Results

During a follow-up period of 35 ± 10 months, 44 out of the 157 stroke patients experienced recurrent strokes. There was significant difference in the incidences of stroke recurrence between IPN Grade 1 and Grade 2 (12.6% vs. 57.4%, p < 0.

SUBMITTER: Huang Z 

PROVIDER: S-EPMC12751885 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature