Diagnostic value of Gd-EOB-DTPA-enhanced MRI versus contrast-enhanced CT for detecting liver metastasis in colorectal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

To compare the diagnostic accuracy of gadoxetate disodium enhanced MRI (EOB-MRI) and contrast-enhanced CT (CE-CT) in the detection of colorectal cancer liver metastases (CRLM).

Methods

We conducted a systematic search of PubMed, Embase, web of science, and the Cochrane Library up to 4 November 2025, to identify original studies comparing the accuracy of EOB-MRI with CE-CT in diagnosing CRLM. Pooled sensitivity (SEN) and specificity (SPE) were calculated, and subgroup analyses were performed based on tumor diameter and ethnicity.

Results

A total of 1,842 patients from 15 studies diagnosed with colorectal cancer were included in the study. The pooled SEN of EOB-MRI was 90.0% [95% confidence interval (CI): 88.0%-92.0%], and the corresponding SPE was 88.0% (95%

SUBMITTER: Chen S 

PROVIDER: S-EPMC12751889 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature