Working memory and its neural characteristics in male schizophrenia patients with or without a history of violent behavior: an exploratory fNIRS study.

ABSTRACT:

Background

Evidence has suggested an association between working memory impairment and violence in people with schizophrenia. However, the neural characteristics of working memory deficit in this patient population remain unclear. This study aimed to examine the neurobiological differences in brain activity using the working memory task in schizophrenia patients with and without a history of violent behavior.

Method

A total of 194 patients, including 106 with a history of severe violent behavior and 88 without such a history, as well as 66 healthy individuals, were recruited. All the participants were required to complete the n-back task (0-, 1-, and 2-back) under functional near-infrared spectroscopy.

Results

Patients with a history of violent behavior, but not those

SUBMITTER: Gu Y 

PROVIDER: S-EPMC12751973 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature