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Validation of China's 2025 high-risk criteria in RT-PCR-confirmed chikungunya inpatients: a single-centre retrospective cohort.


ABSTRACT:

SUBMITTER: Yang S 

PROVIDER: S-EPMC12752012 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature

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Validation of China's 2025 high-risk criteria in RT-PCR-confirmed chikungunya inpatients: a single-centre retrospective cohort.

Yang Shuqi S   Wan Zimei Z   Zhan Liting L   Zhang Huatang H   Lin Yijie Y   Weng Zhangyan Z   Wang Xing X   Su Zhijun Z   Yu Xueping X  

BMC infectious diseases 20251222 1


BACKGROUND: China’s 2025 clinical guideline designates age ≥ 65 years, pregnancy, and chronic comorbidity as patient categories requiring prioritized monitoring; quantitative validation in inpatients is lacking. METHODS: We conducted a single‑centre retrospective cohort including 131 consecutive RT‑PCR-confirmed patients admitted during an imported outbreak (1 August−30 September 2025). Patients meeting any high‑risk criterion were classified as high‑risk. The primary endpoint was length of stay  ...[more]

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