Preoperative CT-based radiomics to predict the 5-year growth of residual nodules after resection of dominant lung tumors in patients with multiple lung subsolid nodules.

ABSTRACT:

Background

The current prediction of postoperative growth in synchronous nodules remaining after surgical resection of dominant lung tumors in patients with multiple subsolid lung nodules is limited. This study aims to assess the efficacy of preoperative CT-based radiomics in predicting the 5-year growth of these residual nodules (RNs), versus models constructed using commonly utilized CT morphological and quantitative features.

Methods

Data from 1392 patients who underwent resection for lung subsolid nodules confirmed as adenocarcinoma or precursor glandular lesions between 2014 and 2018 were retrospectively reviewed. Among the participants, 208 surgical patients with 603 RNs were included, with a follow-up period exceeding five years. Each RN was classified as either grown

SUBMITTER: Fu G 

PROVIDER: S-EPMC12752066 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature