A serial 4-year cross-sectional study of dyslipidemia on Pamirs Plateau, the roof of the world.

ABSTRACT:

Background

Dyslipidemia is a major cardiovascular risk factor; however, disease patterns-particularly lipid profiles-remain understudied in high-altitude populations. On the Pamirs Plateau (> 4000 m), no relevant epidemiological studies have been conducted to date. This study investigates the disease patterns in this region, with an emphasis on dyslipidemia epidemiology.

Methods

We conducted a serial cross-sectional study (2021-2024) using annual health examination data from Tashkurgan County, Pamirs Plateau. Adults aged ≥ 18 years residing ≥ 1 year were included. We first examined the overall disease patterns, with a focus on dyslipidemia. Age-standardized prevalence was calculated and stratified by sex and ethnicity. Subsequently, lipid profile distributions and temporal t

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12752180 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature