Genomic characterization of an environmental Burkholderia thailandensis strain from Kerala, India reveals virulence and antimicrobial resistance signatures.

ABSTRACT:

Background

Burkholderia thailandensis is an environmental Gram-negative bacterium closely related to the highly pathogenic B. pseudomallei, the causative agent of melioidosis. Although B. thailandensis is generally considered avirulent, sporadic human infections and genomic features suggest potential for pathogenic adaptation. We report the whole-genome sequencing and comparative analysis of a B. thailandensis strain (BUR-TH_250524) isolated from soil in Kerala, India, to assess its taxonomic identity, genetic composition, and potential for antimicrobial resistance and virulence. Genomic DNA was extracted from a biochemically identified isolate, which was subsequently confirmed as B. thailandensis through 16S rRNA gene sequencing. Whole-genome sequencing was performed using Illumin

SUBMITTER: Santhosh A 

PROVIDER: S-EPMC12752231 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature