Evaluating the value of circulating miR-21, miR-210 and miR-942 in the diagnosis of early-stage lung adenocarcinoma.

ABSTRACT:

Background

The incidence of lung adenocarcinoma has been gradually increasing in recent years. Its early diagnosis remains challenging. Dysregulation of miRNAs is involved in the development of many malignant tumors, miRNAs have shown potential promise in the early diagnosis of tumors. This study aimed to evaluate the value of serum miR-21, miR-210, and miR-942 expression in the early diagnosis of lung adenocarcinoma(LUAD).

Methods

Preoperative peripheral blood was collected from 155 patients with suspected lung nodules who were due to be operated on, and the serum levels of miR-21, miR-210, and miR-942 were determined by real-time fluorescence quantitative PCR (RT-qPCR). Based on the postoperative pathology results, 130 patients with stage I-II early-stage LUAD were selecte

SUBMITTER: Li R 

PROVIDER: S-EPMC12752317 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature