The epidemiology and clinical features of melioidosis in the Lao PDR: a 21-year prospective hospital-based cohort study.

ABSTRACT:

Background

Melioidosis, caused by Burkholderia pseudomallei, poses a significant health risk in tropical and subtropical regions. The disease is endemic in Southeast Asia, including the Lao PDR (Laos), where the first case was confirmed in 1999. Although diagnostic improvements have led to increased identification of patients, comprehensive clinical and epidemiological data on melioidosis in Laos remain limited.

Methods

We conducted a 21-year prospective study (1999-2020) at Mahosot Hospital and other primary-tertiary hospitals in Vientiane Capital and surrounding provinces. Data were collected for all culture-confirmed melioidosis patients, including demographics, clinical presentations, laboratory findings, and outcomes. The epidemiological and clinical features of melioid

SUBMITTER: Lao Melioidosis Research Group 

PROVIDER: S-EPMC12752390 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature