Associations between sarcopenic obesity and the risk of cardiovascular-kidney-metabolic syndrome progression: insights from the China health and retirement longitudinal study.

ABSTRACT:

Background

This study aimed to explore the association between sarcopenic obesity (SO) and advanced stages of cardiovascular-kidney-metabolic (CKM) syndrome, as well as to prospectively examine its relationship with cardiovascular events in CKM stages 0-3.

Methods

Data were drawn from the China Health and Retirement Longitudinal Study (2011-2020) encompassing a median follow-up of 9.0 years for incident cardiovascular events. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 criteria. Non-sarcopenic participants with optimal body mass index or waist circumference served as the reference group. Outcome was major adverse cardiovascular events (MACEs) defined as a composite of all-cause death, cardiovascular problem, and stroke. Multivariable logis

SUBMITTER: Xin Y 

PROVIDER: S-EPMC12752421 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature