Application of Probe-Capture metagenomics in rabies diagnosis.

ABSTRACT:

Background

Rabies, a lethal viral encephalitis caused by Rabies virus (RabV), is transmitted via bites, scratches, or mucosal contact with infected animals, as well as through inhalation of aerosolized particles, ingestion of contaminated raw animal products, or transplantation of infected organs. It's near-universal fatality, diverse transmission routes, and marked clinical variability significantly impede timely diagnosis, highlighting the demand for a rapid and precise diagnostic approach.

Methods

Single-center retrospective case series.

Results

This series reported three rabies cases admitted to the First People's Hospital of Qinzhou: one without identifiable exposure and two with confirmed exposure histories. Clinical presentations were highly variable and diagno

SUBMITTER: Liu P 

PROVIDER: S-EPMC12752439 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature