An Anisotropic and Stable-Conductance Patch for Mechanical-Electrical Coupling With Infarcted Myocardium.

ABSTRACT: Polymeric conductive patches have conventionally been employed to facilitate the repair of infarcted myocardium by enhancing myocardial electrical conduction and providing mechanical support. However, it remains a challenge to restore the electrical conduction and diastolic-systolic functions with stable and anisotropic mechanical and electrical cues in the dynamic physiological environment. Herein, inspired by the hierarchical myocardial fiber microscopic striated structure, we established a weaving-based processing method to compound a striated polypyrrole conductive coating on the surface of highly oriented elastic fiber bundles. This unique design endows the patch with exceptional stretchability (elongation at break > 400%), stable conductance (ΔR/R ₀ = 0.04 wi

SUBMITTER: Li Y 

PROVIDER: S-EPMC12752566 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature