Dual-parameter risk stratification based on device landing zone calcification and aortic annular perimeter for paravalvular regurgitation after self-expanding TAVR.

ABSTRACT:

Purpose

The study aimed to identify independent predictors associated with paravalvular regurgitation (PVR) after self-expanding transcatheter aortic valve replacement (SE-TAVR) and to develop a dual-parameter risk stratification model.

Methods

This retrospective study enrolled 292 severe aortic stenosis patients underwent SE-TAVR. PVR severity was assessed pre-discharge. Multivariate logistic regression identified independent predictors of mild/moderate PVR, optimal cutoff values for significant anatomical parameters were determined using receiver operating characteristic (ROC) curve analysis. Patients were subsequently stratified into three risk groups based on these thresholds.

Results

Mild/moderate PVR occurred in 24.0 % of patients. Independent predictors include

SUBMITTER: Shu J 

PROVIDER: S-EPMC12752758 | biostudies-literature | 2026 Jun

REPOSITORIES: biostudies-literature