Outcomes in Patients Undergoing Transoral Incisionless Fundoplication With Ineffective Esophageal Motility.

ABSTRACT:

Background

Transoral incisionless fundoplication (TIF) presents a minimally invasive, endoscopic treatment for the management of gastroesophageal reflux disease (GERD), known for its efficacy and safety in patients with normal esophageal motility. However, the use of TIF in ineffective esophageal motility (IEM) remains largely unexplored. This study examined the outcomes of TIF in IEM patients.

Methods

Retrospective data from 164 patients, including 29 with IEM and refractory GERD, were analyzed to obtain assessments of disease-specific quality of life through the Gastroesophageal Reflux Disease Health-Related Quality of Life Questionnaire (GERD-HRQL) and proton pump inhibitor usage.

Results

Statistically significant improvements were seen in total, heart burn, and re

SUBMITTER: Patel D 

PROVIDER: S-EPMC12752835 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature