Prevalence and associating factors for iatrogenic gliosis-like changes in surgically treated intracranial meningioma patients-A retrospective study of 255 meningioma patients.

ABSTRACT:

Purpose

Persistent peritumoral brain edema (PTBE) following surgery of intracranial meningioma (IM) has recently been proposed to represent, in part, iatrogenic gliosis-like changes (IGCs). We aimed to estimate the frequency of IGCs after gross total resection (GTR) of IM, identify factors associated with IGCs, and assess their effect on surgical outcome.

Methods

Patients with IM who underwent surgery between 2000 and 2020, presented with no preoperative PTBE on magnetic resonance imaging, and had at least one year of follow-up were retrospectively identified. Only patients without preoperative PTBE were included to ensure that postoperative hyperintense fluid-attenuated inversion recovery (FLAIR) changes were iatrogenic. Outcomes were evaluated based on postoperative sympto

SUBMITTER: Laajava J 

PROVIDER: S-EPMC12752940 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature