Dengue virus serotype 4 in Aedes aegypti mosquitoes in Kenya.

ABSTRACT: Dengue fever is one of the most globally significant arthropod-borne viral diseases. In 2024, more than 14 million cases and 10,000 deaths were reported across 92 tropical and subtropical countries. Dengue virus (DENV), endemic in Sub-Saharan Africa including Kenya, comprises four serotypes (DENV-1 to DENV-4). While DENV-1 to DENV-3 are widely distributed in the region, DENV-4 is considered rare. However, information on the distribution of DENV serotypes and the genetic diversity within African mosquito populations remains limited. To address this gap, 2,400 Aedes aegypti, the primary vector species of DENV, were collected from southeastern and coastal Kenya between 2016 and 2019 and subjected to viral analyses. Collected samples were screened for orthoflaviviruses using a nested pan-ortho

SUBMITTER: Joensuu R 

PROVIDER: S-EPMC12752982 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature