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Clinical characteristics and risk factors of severe bocavirus-positive pneumonia in children and a literature review.


ABSTRACT: Increasing evidence suggests that human bocavirus (HBoV) is associated with respiratory symptoms in the absence of other identifiable pathogens and may even precipitate severe lower respiratory tract infections. However, only a few studies of severe human bocavirus infections in pediatric patients have been reported. The aim of the current study was to collect and analyze clinical data from children diagnosed with mild pneumonia and severe pneumonia, with an emphasis on those testing positive for HBoV from June 2009 to June 2019. Among the 799 HBoV-positive children included in the study, approximately 5.88% experienced severe pneumonia. Results revealed no significant differences between co-detection and single detection of HBoV-positive pneumonia in the severe and mild groups, supporting

SUBMITTER: Liao J 

PROVIDER: S-EPMC12753018 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature