Cost-effectiveness of open versus laparoscopic pancreaticoduodenectomy: a retrospective Markov model analysis from China.

ABSTRACT:

Introduction

Open pancreaticoduodenectomy (OPD) and laparoscopic pancreaticoduodenectomy (LPD) are the two main surgical approaches for treating pancreatic cancer.

Objective

To evaluate the cost-effectiveness of OPD and LPD in treating pancreatic ductal adenocarcinoma by establishing a Markov Model.

Methods

Patients with pancreatic ductal adenocarcinoma who staged at I-III undergone OPD or LPD were retrospectively included from March 2017 to December 2020. Patients were followed up by telephone until June 2024. A Markov Model was established to simulate disease progression after 120 cycles by including survival data and average hospitalization costs.

Results

Two hundred patients were included, 100 for OPD group and the other 100 for LPD group. The results indic

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12753395 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature