Association between intrinsic capacity, changes in intrinsic capacity, and cardiometabolic multimorbidity: results from three prospective cohort studies.

ABSTRACT:

Background

Intrinsic capacity (IC)is closely associated with cardiometabolic health in middle-aged and older adults. The purpose of this study was to determine the associations of baseline IC, cumulative IC scores, and their dynamic changes with the risk of incident cardiometabolic multimorbidity (CMM).

Methods

Using data from three prospective cohorts, the China Health and Retirement Longitudinal Study (CHARLS), the English Longitudinal Study of Ageing (ELSA), and the Health and Retirement Study (HRS), participants who met the eligibility criteria were included in this study. Kaplan-Meier curves and Cox models analyzed risk trends and associations.

Results

A total of 11,916 participants were included based on the inclusion and exclusion criteria. At baseline, the ris

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12753437 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature