Multifocal transcranial electrical stimulation to enhance cognitive functions: a systematic review.

ABSTRACT:

Background

Multifocal transcranial Electrical Stimulation (tES) has emerged as an innovative approach for modulating cognitive functions by concurrently targeting multiple brain regions. Despite its potential, the efficacy and underlying mechanisms of this technique remain unclear.

Objective

To evaluate the efficacy of multifocal tES in enhancing cognitive function by examining targeted brain regions, stimulation protocols, and behavioral and neurophysiological outcomes.

Methods

A systematic search of PubMed, EMBASE, Cochrane Library, Scopus, and Web of Science databases was conducted up to February 10, 2025, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. The inclusion criteria encompassed human studies utilizing conc

SUBMITTER: Choi JS 

PROVIDER: S-EPMC12753878 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature