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Diagnostic accuracy of lung ultrasound score for bronchopulmonary dysplasia in preterm neonates: a systematic review and meta-analysis.


ABSTRACT:

Background

Bronchopulmonary dysplasia (BPD) remains common among preterm infants, yet diagnostic criteria rely on post-hoc oxygen requirements and radiography. Semiquantitative lung ultrasound (LUS) scoring offers a radiation-free, bedside alternative. We sought to determine the time-dependent diagnostic accuracy of LUS scores for BPD in preterm neonates.

Methods

We performed a systematic review and meta-analysis of studies reporting LUS scores in preterm neonates (born at <37 gestational weeks) with BPD. We searched five databases through June 2025. We stratified data into four postnatal age timepoints (days 1-3, 7, 14, and 21) and pooled them using bivariate random-effects models to estimate sensitivity, specificity, likelihood ratios, diagnostic odds ratios, and area unde

SUBMITTER: Han C 

PROVIDER: S-EPMC12753949 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature