Effects of transcranial direct current stimulation on non-motor functions in individuals with Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Parkinson's disease (PD) is a highly prevalent neurodegenerative disorder that poses a significant mental and physical burden on patients, markedly diminishing their quality of life. This study aimed to systematically evaluate the effects of transcranial direct current stimulation (tDCS) on cognitive functions, mood state, sleep function, and overal quality of life in individuals with PD.

Methods

Relevant literature was sourced from multiple databases, ultimately including 22 studies with a total of 1324 individuals. Data analysis was conducted using meta-analysis software. The protocol was registered in PROSPERO (CRD42024599943).

Results

The findings indicated that tDCS significantly enhanced cognitive function, alleviated anxiety and depression, increased

SUBMITTER: Li Q 

PROVIDER: S-EPMC12753959 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature