Global research trends in signaling pathways of spasmolytic polypeptide-expressing metaplasia pathogenesis: a bibliometric analysis.

ABSTRACT:

Background

Signaling pathways associated with spasmolytic polypeptide-expressing metaplasia (SPEM) pathogenesis play a critical role in disease development, particularly in gastric cancer precursor lesions. However, global research trends in signaling pathways in SPEM pathogenesis remain undetermined. This study aims to fill this gap by conducting a comprehensive bibliometric analysis to map the field, identify key insights, and guide future research directions.

Methods

Articles and reviews were retrieved from the Web of Science Core Collection up to June 8 2025. Bibliometric analysis and knowledge mapping were conducted via CiteSpace and VOSviewer.

Results

A total of 89 papers from 221 institutions, 719 authors, and 56 journals across 21 countries/regions were includ

SUBMITTER: Xu Q 

PROVIDER: S-EPMC12754180 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature