Incidence, Clinical Risk Factors, and Pregnancy Outcomes of Trophectoderm- and Inner Cell Mass-Poor-Quality Blastocysts in Single Blastocyst Transfer Cycles: A Retrospective Cohort Study.

ABSTRACT:

Purpose

To study incidence, clinical risk factors, and pregnancy outcomes of trophectoderm- and inner cell mass-poor-quality blastocysts in single blastocyst transfer cycles.

Design

A retrospective cohort study included patients who underwent their first single blastocyst transfer cycle. A multivariate log-binomial regression model with COPY methods was performed.

Results

The incidence of having no transferable high-quality blastocysts was 33.8% (15 685/46 433). Maternal age, BMI, infertility duration, cycle number, embryo developmental stage, and transfer strategies are independent risk factors that affect the quality of blastocysts (p < 0.05). After adjusting for 11 confounding factors, the CPR and LBR significantly decreased across the groups in the order of

SUBMITTER: Chen L 

PROVIDER: S-EPMC12754268 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature