Association of hemoglobin glycation index with all-cause mortality in critically ill patients with atrial fibrillation: a retrospective analysis from MIMIC-IV.

ABSTRACT:

Background

Atrial fibrillation (AF) is recognized as the most prevalent sustained cardiac arrhythmia encountered in clinical practice, particularly among critically ill patients, and is correlated with heightened mortality rates. The hemoglobin glycation index (HGI), which captures interindividual variability in hemoglobin glycation, has emerged as a promising metabolic marker with potential prognostic significance. Nonetheless, the relationship between HGI and mortality in critically ill patients with AF remains to be elucidated.

Methods

This retrospective cohort study utilized the MIMIC-IV database (version 3.1) and included 3,157 critically ill patients with AF. Patients were stratified into tertiles based on HGI levels: T1 (≤-0.505), T2 (-0.505 to 0.035), and T3 (> 0.035

SUBMITTER: Wu C 

PROVIDER: S-EPMC12754970 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature