Seasonally varying effects of improved water, sanitation and handwashing interventions on Giardia infection in Bangladesh.

ABSTRACT:

Background

Giardia is the most common enteric parasite among children in low-resource settings, causing diarrhoea and leading to prolonged infection or asymptomatic carriage. We assessed whether the effect of water, sanitation and handwashing (WSH) interventions on Giardia infection among rural Bangladeshi children varies with seasonal conditions.

Methods

We conducted a secondary analysis of the WASH Benefits Bangladesh cluster-randomized trial, with 450 clusters assigned to four arms in a 2×2 factorial design (WSH: WSH, WSH+Nutrition; no WSH: Control, Nutrition). Giardia infection was measured by multiplex real-time PCR in stool samples after two years of intervention. Effects were estimated by marginal treatment and assessed for heterogeneity by season

SUBMITTER: Ante-Testard PA 

PROVIDER: S-EPMC12755254 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature