Cigarette smoking, opioid consumption, and pain intensity after major surgery: An observational study.

ABSTRACT:

Background

Chronic exposure to nicotine may change pain perception and promote opioid intake. This study aimed to evaluate the putative effect of cigarette smoking on opioid requirements and pain intensity after surgery.

Methods

Patients who underwent major surgery and received intravenous patient-controlled analgesia (IV-PCA) at a medical center between January 2020 and March 2022 were enrolled. Patients' preoperative smoking status was assessed using a questionnaire by certified nurse anesthetists. The primary outcome was postoperative opioid consumption within 3 days after surgery. The secondary outcome was the mean daily maximum pain score, assessed using a self-report 11-point numeric rating scale, and the number of IV-PCA infusion requests within three postoperative da

SUBMITTER: Wang YC 

PROVIDER: S-EPMC12755550 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature