Factors associated with enrollment in a randomized clinical trial of docosahexaenoic supplementation in toddlers born preterm.

ABSTRACT: Background/aimsTo assess pre- and postnatal factors associated with participation in a randomized clinical trial of daily docosahexaenoic supplementation in toddlers born preterm. We hypothesized that enrolled families would not differ from those who did not participate.MethodChildren eligible for the Omega Tots trial were born at <35 completed weeks' gestation and were 10-16 months of age at recruitment. Eligibility data abstracted from the medical record were linked with the child's birth certificate. The primary outcome was whether the family enrolled, declined, or was non-responsive to recruitment efforts. Log-binomial regression calculated risk ratios (RR).Results316 families enrolled, 1089 declined, and 1081 were non-responsive. Enrolling, rather than not enrolling, was negatively as

SUBMITTER: Boone KM 

PROVIDER: S-EPMC12755725 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature