Whole-genome sequencing of Burkholderia glumae strains from Thailand reveals potential horizontal gene transfer with Burkholderia pseudomallei.

ABSTRACT: Burkholderia glumae is an emerging phytopathogen that causes bacterial panicle blight in rice and has been implicated in rare human infections. In Thailand, B. glumae and the human pathogen Burkholderia pseudomallei coexist in rice fields. Given the high genomic plasticity of Burkholderia species, including frequent genome rearrangements, variability in mobile genetic elements, and recombination events that facilitate horizontal gene transfer, there are concerns about the emergence of novel traits that may affect both plant and human health. In this study, we performed whole-genome sequencing and a comparative genomic analysis of 16 B. glumae strains isolated from rice fields across seven Thai provinces. Our phylogenomic analysis, based on core-genome single-nucleotide polymorphisms, revea

SUBMITTER: Patarapuwadol S 

PROVIDER: S-EPMC12755741 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature