Endemic and zoonotic cycles of cutaneous leishmaniasis depend on vector feeding preferences: An epidemiological model for Southeastern Mexico.

ABSTRACT:

Introduction

Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by Leishmania spp. parasites. It poses significant public health challenges among economically marginalized communities in endemic regions like Southeastern Mexico. Here, we developed a mathematical model to describe the transmission dynamics of CL in the Yucatan Peninsula region, focusing on two key sand fly vectors: Lutzomyia cruciata and Bichromomyia olmeca.

Methods

Transmission was modelled as frequency dependent with Susceptible-Infected dynamics for vectors and rodents, and Susceptible-Exposed-Infected-Susceptible for humans, and accounts for the impact of available blood meals on vector populations. The model was parameterized from published literature for vector and reservoir growth rate

SUBMITTER: Martin G 

PROVIDER: S-EPMC12755797 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature